HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: LAMP2 (P13473)
Lysosome-associated membrane glycoprotein 2 (LAMP-2) (Lysosome-associated membrane protein 2) (CD107 antigen-like family member B) (LGP-96) (CD antigen CD107b)
Gene: LAMP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 23503679
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0019899 - enzyme binding GO:0043231 - intracellular membrane-bounded organelle GO:0048471 - perinuclear region of cytoplasm and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 410
+	Hs
		522736 SRC_HUMAN (1-510): 0: 580: 51.97		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		411972 FYN_HUMAN (1-510): 0: 576: 54.12		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		433233 YES_HUMAN (1-510): 0: 572: 54.26		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		433542 LYN_HUMAN (1-512): 0: 611: 100.00		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		506858 SRC_HUMAN (1-510): 0: 580: 51.97		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		433228 YES_HUMAN (1-510): 0: 572: 54.26		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		434087 LYN_HUMAN (1-512): 0: 611: 100.00		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95
+	Hs
		523214 SRC_HUMAN (1-510): 0: 580: 51.97		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95
+	Hs
		433509 YES_HUMAN (1-510): 0: 572: 54.26		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95