HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0045121 - membrane raft GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 512 Hs			1 205
+	Hs
		434007 LYN_HUMAN (1-512): 0: 611: 100.00		RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59
+	Hs
		433685 LYN_HUMAN (1-512): 0: 611: 100.00		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		433673 LYN_HUMAN (1-512): 0: 611: 100.00		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		433677 LYN_HUMAN (1-512): 0: 611: 100.00		RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75
+	Hs
		433556 LYN_HUMAN (1-512): 0: 611: 100.00		RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03
+	Hs
		433671 LYN_HUMAN (1-512): 0: 611: 100.00		RAC3_HUMAN (10-183): 9.1e-76: 227: 66.67
+	Hs
		433681 LYN_HUMAN (1-512): 0: 611: 100.00		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51
+	Hs
		433524 LYN_HUMAN (1-512): 0: 611: 100.00		RHOC_HUMAN (1-192): 1.16e-74: 225: 50.52
+	Hs
		433244 YES_HUMAN (1-510): 0: 572: 54.26		RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00
+	Hs
		522888 SRC_HUMAN (1-510): 0: 580: 51.97		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		412123 FYN_HUMAN (1-510): 0: 576: 54.12		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		412113 FYN_HUMAN (1-510): 0: 576: 54.12		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		522885 SRC_HUMAN (1-510): 0: 580: 51.97		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51
+	Hs
		412115 FYN_HUMAN (1-510): 0: 576: 54.12		RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75
+	Hs
		411980 FYN_HUMAN (1-510): 0: 576: 54.12		RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03
+	Hs
		412120 FYN_HUMAN (1-510): 0: 576: 54.12		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51
+	Hs
		411948 FYN_HUMAN (1-510): 0: 576: 54.12		RHOC_HUMAN (1-192): 1.16e-74: 225: 50.52
+	Hs
		433239 YES_HUMAN (1-510): 0: 572: 54.26		RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03
+	Hs
		433304 YES_HUMAN (1-510): 0: 572: 54.26		RAC3_HUMAN (10-183): 9.1e-76: 227: 66.67
+	Hs
		433217 YES_HUMAN (1-510): 0: 572: 54.26		RHOC_HUMAN (1-192): 1.16e-74: 225: 50.52