HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: FCAR (P24071)
Immunoglobulin alpha Fc receptor (IgA Fc receptor) (CD antigen CD89)
Gene: FCAR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	9427690
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 287
+	Hs
		434021 LYN_HUMAN (1-512): 0: 611: 100.00		GPVI_HUMAN (1-284): 1.49e-50: 171: 31.34
+	Hs
		442886 HCK_HUMAN (1-512): 0: 595: 70.70		GPVI_HUMAN (1-284): 1.49e-50: 171: 31.34
+	Hs
		433545 LYN_HUMAN (1-512): 0: 611: 100.00		FCG2A_HUMAN (22-276): 2.07e-44: 154: 19.07
+	Hs
		433610 LYN_HUMAN (1-512): 0: 611: 100.00		FCG2B_HUMAN (7-222): 2.99e-43: 151: 17.73
+	Hs
		412364 FYN_HUMAN (1-510): 0: 576: 54.12		GPVI_HUMAN (1-284): 1.49e-50: 171: 31.34
+	Hs
		433481 YES_HUMAN (1-510): 0: 572: 54.26		GPVI_HUMAN (1-284): 1.49e-50: 171: 31.34
+	Hs
		522812 SRC_HUMAN (1-510): 0: 580: 51.97		FCG2C_HUMAN (7-276): 1.53e-47: 162: 18.25
+	Hs
		412048 FYN_HUMAN (1-510): 0: 576: 54.12		FCG2C_HUMAN (7-276): 1.53e-47: 162: 18.25
+	Hs
		519400 SRC_HUMAN (1-510): 0: 580: 51.97		FCERA_HUMAN (1-256): 6.58e-45: 154: 19.62
+	Hs
		522811 SRC_HUMAN (1-510): 0: 580: 51.97		FCG2B_HUMAN (7-222): 2.99e-43: 151: 17.73
+	Hs
		412047 FYN_HUMAN (1-510): 0: 576: 54.12		FCG2B_HUMAN (7-222): 2.99e-43: 151: 17.73
+	Hs
		434111 LYN_HUMAN (1-512): 0: 611: 100.00		ROBO1_HUMAN (120-273): 1.05e-20: 94: 12.65
+	Hs
		434019 LYN_HUMAN (1-512): 0: 611: 100.00		ROBO2_HUMAN (120-273): 2.06e-20: 93.2: 12.65
+	Mm
		639442 LYN_MOUSE (1-512): 0: 612: 96.09		LIRB3_MOUSE (29-129): 1.17e-12: 69.8: 15.74
+	Dm
		219802 ABL_DROME (3-508): 3.3e-170: 523: 36.36		O44924_DROME (18-235): 4.49e-37: 141: 14.35
+	Mm
		435881 HCK_MOUSE (1-512): 0: 592: 69.92		LIRB3_MOUSE (29-129): 1.17e-12: 69.8: 15.74
+	Hs
		986398 BTK_HUMAN (2-505): 1.48e-156: 462: 33.86		GPVI_HUMAN (1-284): 1.49e-50: 171: 31.34
+	Hs
		782807 CSK_HUMAN (64-503): 1.5e-171: 493: 38.41		LIRB1_HUMAN (21-215): 3.72e-28: 115: 25.12
+	Hs
		782798 CSK_HUMAN (64-503): 1.5e-171: 493: 38.41		LAIR1_HUMAN (121-234): 6.81e-23: 97.1: 22.50