HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: MARCS (P29966)
Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)
Gene: MARCKS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 332
+	Hs
		297808 LYN_HUMAN (1-512): 0: 611: 100.00		K0754_HUMAN (52-332): 1.35e-14: 77.1: 16.38
+	Hs
		433560 LYN_HUMAN (1-512): 0: 611: 100.00		MUC1_HUMAN (68-331): 2.42e-11: 66.7: 10.57
+	Hs
		433954 LYN_HUMAN (1-512): 0: 611: 100.00		PRAM_HUMAN (3-330): 8.13e-11: 64.8: 11.68
+	Hs
		166024 FYN_HUMAN (1-510): 0: 576: 54.12		SYNJ2_HUMAN (63-316): 5.31e-21: 96: 9.20
+	Hs
		433267 YES_HUMAN (1-510): 0: 572: 54.26		MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00
+	Hs
		203198 LCK_HUMAN (1-512): 0: 582: 63.62		SYNJ1_HUMAN (8-329): 5.64e-12: 69.1: 9.41
+	Hs
		411582 LCK_HUMAN (1-512): 0: 582: 63.62		MUC1_HUMAN (68-331): 2.42e-11: 66.7: 10.57
+	Hs
		522749 SRC_HUMAN (1-510): 0: 580: 51.97		MUC1_HUMAN (68-331): 2.42e-11: 66.7: 10.57
+	Hs
		412362 FYN_HUMAN (1-510): 0: 576: 54.12		MAGE1_HUMAN (3-326): 4.56e-11: 66: 11.66
+	Hs
		412433 FYN_HUMAN (1-510): 0: 576: 54.12		MYO16_HUMAN (64-325): 5.72e-10: 62.9: 10.03
+	Hs
		166023 ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88		SYNJ2_HUMAN (63-316): 5.31e-21: 96: 9.20
+	Hs
		337335 ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88		MUC1_HUMAN (68-331): 2.42e-11: 66.7: 10.57