Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: TNFL6 (P48023)
Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand) (APTL) (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]
Gene: FASLG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.613

The method score is based on:

Property Details
Experiments 17164290, 19807924
Identification Methods pull down, unspecified method, phage display
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005102 - signaling receptor binding
GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0008284 - positive regulation of cell population proliferation
and 2 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 512
Hs

1 281
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Last updated: 15 Jul 2024