HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0048471 - perinuclear region of cytoplasm GO:0070062 - extracellular exosome GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 512 Hs			1 192
+	Hs
		433685 LYN_HUMAN (1-512): 0: 611: 100.00		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		433556 LYN_HUMAN (1-512): 0: 611: 100.00		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		434007 LYN_HUMAN (1-512): 0: 611: 100.00		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Hs
		433673 LYN_HUMAN (1-512): 0: 611: 100.00		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		433677 LYN_HUMAN (1-512): 0: 611: 100.00		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		433524 LYN_HUMAN (1-512): 0: 611: 100.00		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		433565 LYN_HUMAN (1-512): 0: 611: 100.00		RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49
+	Hs
		522888 SRC_HUMAN (1-510): 0: 580: 51.97		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		412123 FYN_HUMAN (1-510): 0: 576: 54.12		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		433314 YES_HUMAN (1-510): 0: 572: 54.26		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		411980 FYN_HUMAN (1-510): 0: 576: 54.12		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		433239 YES_HUMAN (1-510): 0: 572: 54.26		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		433304 YES_HUMAN (1-510): 0: 572: 54.26		RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00
+	Hs
		412113 FYN_HUMAN (1-510): 0: 576: 54.12		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		412115 FYN_HUMAN (1-510): 0: 576: 54.12		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		433305 YES_HUMAN (1-510): 0: 572: 54.26		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		433307 YES_HUMAN (1-510): 0: 572: 54.26		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		411948 FYN_HUMAN (1-510): 0: 576: 54.12		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		433217 YES_HUMAN (1-510): 0: 572: 54.26		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		433244 YES_HUMAN (1-510): 0: 572: 54.26		RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49