HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: AKA12 (Q02952)
A-kinase anchor protein 12 (AKAP-12) (A-kinase anchor protein 250 kDa) (AKAP 250) (Gravin) (Myasthenia gravis autoantigen)
Gene: AKAP12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 1782
+	Hs
		442810 HCK_HUMAN (1-512): 0: 595: 70.70		AKA12_HUMAN (1-1782): 0: 676: 100.00
+	Hs
		522923 SRC_HUMAN (1-510): 0: 580: 51.97		AKA12_HUMAN (1-1782): 0: 676: 100.00
+	Hs
		788977 TEC_HUMAN (35-505): 1.09e-160: 472: 35.48		MAP1B_HUMAN (3-1107): 1.08e-90: 331: 8.57
+	Hs
		152571 ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88		KMT2D_HUMAN (47-764): 3.85e-43: 176: 11.48
+	Hs
		434084 LYN_HUMAN (1-512): 0: 611: 100.00		SRRM2_HUMAN (4-1096): 6.49e-11: 70: 7.25
+	Hs
		522847 SRC_HUMAN (1-510): 0: 580: 51.97		KI67_HUMAN (1-1782): 2.94e-11: 71.2: 11.31
+	Hs
		412078 FYN_HUMAN (1-510): 0: 576: 54.12		KI67_HUMAN (1-1782): 2.94e-11: 71.2: 11.31
+	Hs
		789101 FRK_HUMAN (32-506): 0: 528: 48.47		KI67_HUMAN (1-1782): 2.94e-11: 71.2: 11.31
+	Hs
		337387 ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88		KI67_HUMAN (1-1782): 2.94e-11: 71.2: 11.31
+	Hs
		996575 ITK_HUMAN (35-503): 3.09e-162: 475: 35.83		SRRM2_HUMAN (4-1096): 6.49e-11: 70: 7.25