Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN
Interactor 2: TIAM1 (Q13009)
Rho guanine nucleotide exchange factor TIAM1 (T-lymphoma invasion and metastasis-inducing protein 1) (TIAM-1)
Gene: TIAM1
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 34079125 |
| Identification Methods | proximity labelling technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~PK_Tyr_Ser-Thr, PH~SH3_1, RhoGEF~SH3_1 |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008284 - positive regulation of cell population proliferation GO:0030335 - positive regulation of cell migration GO:0048013 - ephrin receptor signaling pathway and 2 others more... |
| Homologous interactions | 16 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
