HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: CYFP1 (Q7L576)
Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1)
Gene: CYFIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 36736316
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 1253
+	Hs
		433941 LYN_HUMAN (1-512): 0: 611: 100.00		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		523037 SRC_HUMAN (1-510): 0: 580: 51.97		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		433396 YES_HUMAN (1-510): 0: 572: 54.26		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		523107 SRC_HUMAN (1-510): 0: 580: 51.97		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		433444 YES_HUMAN (1-510): 0: 572: 54.26		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		788999 TEC_HUMAN (35-505): 1.09e-160: 472: 35.48		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		789002 TEC_HUMAN (35-505): 1.09e-160: 472: 35.48		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Dm
		337659 ABL_DROME (3-508): 3.3e-170: 523: 36.36		CYFIP_DROME (1-1253): 0: 1903: 65.73