HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: PHLB2 (Q86SQ0)
Pleckstrin homology-like domain family B member 2 (Protein LL5-beta)
Gene: PHLDB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr, PH~SH3_1
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 1253
+	Hs
		433620 LYN_HUMAN (1-512): 0: 611: 100.00		MYH9_HUMAN (242-1165): 8.89e-36: 150: 10.57
+	Hs
		412058 FYN_HUMAN (1-510): 0: 576: 54.12		MYH9_HUMAN (242-1165): 8.89e-36: 150: 10.57
+	Hs
		111443 J3QRU1_HUMAN (1-510): 0: 572: 54.26		MYH9_HUMAN (242-1165): 8.89e-36: 150: 10.57
+	Hs
		433272 YES_HUMAN (1-510): 0: 572: 54.26		MYH9_HUMAN (242-1165): 8.89e-36: 150: 10.57
+	Hs
		297808 LYN_HUMAN (1-512): 0: 611: 100.00		K0754_HUMAN (42-1075): 9.75e-20: 98.6: 8.66
+	Hs
		724720 BLK_HUMAN (1-512): 0: 544: 60.00		MYH9_HUMAN (242-1165): 8.89e-36: 150: 10.57
+	Hs
		433558 LYN_HUMAN (1-512): 0: 611: 100.00		DESP_HUMAN (412-840): 2.66e-10: 67.3: 19.03
+	Hs
		523231 SRC_HUMAN (1-510): 0: 580: 51.97		MYH4_HUMAN (191-846): 2.6e-18: 93.5: 8.75
+	Hs
		411765 LCK_HUMAN (1-512): 0: 582: 63.62		PHLB3_HUMAN (507-808): 8.68e-13: 74.7: 22.33
+	Hs
		411581 LCK_HUMAN (1-512): 0: 582: 63.62		DESP_HUMAN (412-840): 2.66e-10: 67.3: 19.03
+	Hs
		411983 FYN_HUMAN (1-510): 0: 576: 54.12		DESP_HUMAN (412-840): 2.66e-10: 67.3: 19.03