Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN
Interactor 2: ARG28 (Q8N1W1)
Rho guanine nucleotide exchange factor 28 (190 kDa guanine nucleotide exchange factor) (p190-RhoGEF) (p190RhoGEF) (Rho guanine nucleotide exchange factor)
Gene: ARHGEF28
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32707033 |
| Identification Methods | affinity chromatography technology, pull down |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1_1~PK_Tyr_Ser-Thr, C1_1~SH2, RhoGEF~SH3_1 |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0048013 - ephrin receptor signaling pathway |
| Homologous interactions | 14 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
