HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	31391242
Identification Methods	two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 512 Hs			1 548
+	Hs
		412344 FYN_HUMAN (1-510): 0: 576: 54.12		TRI55_HUMAN (1-548): 6.44e-121: 368: 100.00
+	Hs
		433933 LYN_HUMAN (1-512): 0: 611: 100.00		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		433741 LYN_HUMAN (1-512): 0: 611: 100.00		TIF1B_HUMAN (18-534): 7.29e-67: 233: 15.37
+	Hs
		412294 FYN_HUMAN (1-510): 0: 576: 54.12		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		412363 FYN_HUMAN (1-510): 0: 576: 54.12		TRI39_HUMAN (17-414): 4.23e-77: 254: 15.74
+	Hs
		442893 HCK_HUMAN (1-512): 0: 595: 70.70		TRIM1_HUMAN (17-367): 3.2e-63: 222: 21.28
+	Hs
		442773 HCK_HUMAN (1-512): 0: 595: 70.70		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		522958 SRC_HUMAN (1-510): 0: 580: 51.97		TIF1B_HUMAN (18-534): 7.29e-67: 233: 15.37
+	Hs
		523138 SRC_HUMAN (1-510): 0: 580: 51.97		TRIM7_HUMAN (21-436): 1.63e-68: 231: 14.74
+	Hs
		412173 FYN_HUMAN (1-510): 0: 576: 54.12		TIF1B_HUMAN (18-534): 7.29e-67: 233: 15.37
+	Hs
		433340 YES_HUMAN (1-510): 0: 572: 54.26		TIF1B_HUMAN (18-534): 7.29e-67: 233: 15.37
+	Hs
		433465 YES_HUMAN (1-510): 0: 572: 54.26		TRIM5_HUMAN (13-396): 3.08e-68: 230: 14.32
+	Hs
		411977 FYN_HUMAN (1-510): 0: 576: 54.12		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		337563 ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88		TRI39_HUMAN (17-414): 4.23e-77: 254: 15.74
+	Hs
		846541 BLK_HUMAN (1-512): 0: 544: 60.00		TRIM1_HUMAN (17-367): 3.2e-63: 222: 21.28
+	Ce
		220211 SRC2_CAEEL (1-510): 0: 530: 45.74		NHL1_CAEEL (1-517): 2.07e-62: 223: 17.32
+	Ce
		106656 SRC1_CAEEL (1-511): 3.84e-176: 507: 42.29		NHL1_CAEEL (1-517): 2.07e-62: 223: 17.32
+	Hs
		433982 LYN_HUMAN (1-512): 0: 611: 100.00		FSD1L_HUMAN (168-326): 1.27e-13: 75.5: 29.56
+	Hs
		433394 YES_HUMAN (1-510): 0: 572: 54.26		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		789076 ABL2_HUMAN (14-509): 1.38e-171: 517: 36.61		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39