HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.895

Property	Details
Experiments	26496610, 31586073, 33961781, 36526897
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr, PH~SH3_1
Common GO terms	GO:0002244 - hematopoietic progenitor cell differentiation GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 1124
+	Hs
		442889 HCK_HUMAN (1-512): 0: 595: 70.70		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		523166 SRC_HUMAN (1-510): 0: 580: 51.97		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		412369 FYN_HUMAN (1-510): 0: 576: 54.12		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		111446 J3QRU1_HUMAN (1-510): 0: 572: 54.26		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		433483 YES_HUMAN (1-510): 0: 572: 54.26		ANLN_HUMAN (1-1124): 0: 1520: 100.00