Interactor 1: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET
Interactor 2: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.72 | 1.00 | 0.849 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Cadherin~Cadherin, Cadherin~RET_CLD1, Cadherin~RET_CLD3, Cadherin~RET_CLD4, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, RET_CLD1~RET_CLD4, RET_CLD3~RET_CLD4 |
Common GO terms | GO:0000165 - MAPK cascade GO:0001657 - ureteric bud development GO:0001755 - neural crest cell migration GO:0001838 - embryonic epithelial tube formation GO:0004713 - protein tyrosine kinase activity and 45 others more... |
Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024