HitPredict

Interactor 1: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Interactor 2: WDR44 (Q5JSH3)
WD repeat-containing protein 44 (Rab11-binding protein) (Rab11BP) (Rabphilin-11)
Gene: WDR44

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010008 - endosome membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1114 Hs			1 913
+	Hs
		508047 FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61		WDR44_HUMAN (1-913): 0: 589: 100.00
+	Hs
		338528 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		WDR44_HUMAN (1-913): 0: 589: 100.00
+	Hs
		608001 FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89		WDR44_HUMAN (1-913): 0: 589: 100.00
+	Hs
		383588 ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93		GBB3_HUMAN (396-634): 3.01e-31: 127: 9.88
+	Hs
		609202 FGFR3_HUMAN (501-1061): 4.63e-147: 462: 33.16		LIS1_HUMAN (818-912): 3.83e-16: 83.7: 16.16
+	Hs
		338250 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		GBB2_HUMAN (778-911): 6.81e-17: 84.9: 12.68
+	Hs
		383728 ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93		GBB2_HUMAN (778-911): 6.81e-17: 84.9: 12.68
+	Hs
		385480 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		TBL1R_HUMAN (407-585): 2.07e-18: 91.8: 13.41
+	Hs
		384596 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		WDR5_HUMAN (816-912): 5.98e-19: 91: 11.88
+	Hs
		383677 ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93		LIS1_HUMAN (818-912): 3.83e-16: 83.7: 16.16
+	Hs
		384438 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		LIS1_HUMAN (818-912): 3.83e-16: 83.7: 16.16
+	Hs
		384037 ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93		FBW1A_HUMAN (826-911): 6.76e-11: 67.9: 7.96
+	Hs
		383985 ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93		GBB4_HUMAN (406-539): 1.89e-10: 65.6: 10.45
+	Hs
		729704 VGFR2_HUMAN (344-1105): 2.13e-137: 451: 23.91		FBW1A_HUMAN (826-911): 6.76e-11: 67.9: 7.96
+	Hs
		921579 NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19		GBB2_HUMAN (778-911): 6.81e-17: 84.9: 12.68
+	Hs
		1081608 NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19		GBB4_HUMAN (406-539): 1.89e-10: 65.6: 10.45
+	Hs
		572595 VGFR1_HUMAN (716-1026): 5.28e-79: 285: 41.71		LIS1_HUMAN (818-912): 3.83e-16: 83.7: 16.16
+	Hs
		738171 FLT3_HUMAN (714-1014): 2.21e-72: 262: 40.00		LIS1_HUMAN (818-912): 3.83e-16: 83.7: 16.16
+	Hs
		427016 CSF1R_HUMAN (706-1018): 4.91e-74: 267: 40.22		FBW1A_HUMAN (826-911): 6.76e-11: 67.9: 7.96