HitPredict

Interactor 1: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Interactor 2: NT2NA (Q7Z3S9)
Notch homolog 2 N-terminal-like protein A (Notch homolog 2 N-terminal-like protein)
Gene: NOTCH2NLA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.654

The method score is based on:

Property Details
Experiments 25416956, 25910212
Identification Methods two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array, two hybrid bait and prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005509 - calcium ion binding
GO:0007411 - axon guidance
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1114
Hs

1 236
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024