HitPredict

Interactor 1: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Interactor 2: GCP60 (Q9H3P7)
Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi complex-associated protein 1) (GOCAP1) (Golgi phosphoprotein 1) (GOLPH1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7) [Cleaved into: Golgi resident protein GCP60, N-terminally processed]
Gene: ACBD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1114 Hs			1 528
+	Hs
		601591 FGFR2_HUMAN (501-1065): 3.92e-155: 484: 33.11		GCP60_HUMAN (1-528): 0: 594: 100.00
+	Hs
		508193 FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61		GCP60_HUMAN (1-528): 0: 594: 100.00
+	Hs
		609535 FGFR3_HUMAN (501-1061): 4.63e-147: 462: 33.16		GCP60_HUMAN (1-528): 0: 594: 100.00
+	Hs
		338970 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		GCP60_HUMAN (1-528): 0: 594: 100.00
+	Hs
		383975 ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93		GCP60_HUMAN (1-528): 0: 594: 100.00
+	Hs
		385513 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		GCP60_HUMAN (1-528): 0: 594: 100.00
+	Hs
		169204 MUSK_HUMAN (396-1018): 1.21e-135: 434: 25.28		GCP60_HUMAN (1-528): 0: 594: 100.00
+	Hs
		1083892 NTRK2_HUMAN (590-1018): 1.26e-124: 403: 30.74		GCP60_HUMAN (1-528): 0: 594: 100.00
+	Hs
		608124 FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89		GCP60_HUMAN (1-528): 0: 594: 100.00
+	Hs
		1081603 NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19		GCP60_HUMAN (1-528): 0: 594: 100.00
+	Hs
		729356 VGFR3_HUMAN (677-1012): 1.84e-76: 278: 41.25		GCP60_HUMAN (1-528): 0: 594: 100.00