HitPredict

Interactor 1: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Interactor 2: PDLI7 (Q9NR12)
PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma)
Gene: PDLIM7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	12176011, 24466333
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1114 Hs			1 457
+	Hs
		338853 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		PRIC1_HUMAN (261-449): 2.44e-62: 218: 27.78
+	Hs
		508136 FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61		LPP_HUMAN (85-457): 5.09e-56: 197: 19.02
+	Hs
		339088 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		LIMD1_HUMAN (78-457): 6.82e-53: 190: 17.84
+	Hs
		338117 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		PAXI_HUMAN (185-396): 1.45e-33: 135: 21.23
+	Hs
		729669 VGFR2_HUMAN (344-1105): 2.13e-137: 451: 23.91		ZN397_HUMAN (78-329): 5.38e-31: 126: 7.66
+	Hs
		385342 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		PDLI5_HUMAN (1-282): 6.17e-28: 118: 24.82
+	Hs
		1081638 NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19		LIMD1_HUMAN (78-457): 6.82e-53: 190: 17.84
+	Hs
		609281 FGFR3_HUMAN (501-1061): 4.63e-147: 462: 33.16		FHL3_HUMAN (304-449): 9.17e-16: 79.3: 28.38
+	Hs
		508024 FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61		ZYX_HUMAN (74-336): 8.74e-11: 66.1: 13.87
+	Hs
		383792 ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93		FHL3_HUMAN (304-449): 9.17e-16: 79.3: 28.38
+	Hs
		609300 FGFR3_HUMAN (501-1061): 4.63e-147: 462: 33.16		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42
+	Hs
		338473 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42
+	Hs
		385662 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		ZN629_HUMAN (75-420): 3.53e-11: 67.7: 7.21
+	Hs
		383824 ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42
+	Mm
		710146 FAK1_MOUSE (620-1076): 4.7e-105: 356: 27.04		PAXI_MOUSE (61-396): 6.96e-34: 135: 17.49
+	Hs
		607962 FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89		FHL3_HUMAN (304-449): 9.17e-16: 79.3: 28.38
+	Mm
		710149 FAK1_MOUSE (620-1076): 4.7e-105: 356: 27.04		LPXN_MOUSE (96-398): 1.03e-27: 115: 16.83
+	Hs
		607981 FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42
+	Hs
		1076407 NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42
+	Hs
		572633 VGFR1_HUMAN (716-1026): 5.28e-79: 285: 41.71		FHL3_HUMAN (304-449): 9.17e-16: 79.3: 28.38