HitPredict

Interactor 1: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Interactor 2: BAIP2 (Q9UQB8)
BAR/IMD domain-containing adapter protein 2 (Brain-specific angiogenesis inhibitor 1-associated protein 2) (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53)
Gene: BAIAP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32062451
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043025 - neuronal cell body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1114 Hs			1 552
+	Hs
		508271 FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61		BAIP2_HUMAN (1-552): 7.45e-143: 425: 100.00
+	Hs
		609616 FGFR3_HUMAN (501-1061): 4.63e-147: 462: 33.16		BAIP2_HUMAN (1-552): 7.45e-143: 425: 100.00
+	Hs
		339150 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		BAIP2_HUMAN (1-552): 7.45e-143: 425: 100.00
+	Hs
		385734 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		BAIP2_HUMAN (1-552): 7.45e-143: 425: 100.00
+	Hs
		508254 FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61		BI2L1_HUMAN (3-529): 1.57e-106: 330: 39.85
+	Hs
		339097 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		BI2L1_HUMAN (3-529): 1.57e-106: 330: 39.85
+	Hs
		508265 FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61		PACN2_HUMAN (3-436): 4.17e-62: 213: 15.61
+	Hs
		339132 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		PACN2_HUMAN (3-436): 4.17e-62: 213: 15.61
+	Hs
		297957 FGFR3_HUMAN (501-1061): 4.63e-147: 462: 33.16		FCSD2_HUMAN (36-512): 3.35e-41: 160: 12.94
+	Hs
		338405 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		SPTN1_HUMAN (3-442): 2.09e-42: 165: 11.85
+	Hs
		1083909 NTRK2_HUMAN (590-1018): 1.26e-124: 403: 30.74		PACN2_HUMAN (3-436): 4.17e-62: 213: 15.61
+	Hs
		384810 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		SPTN1_HUMAN (3-442): 2.09e-42: 165: 11.85
+	Hs
		609289 FGFR3_HUMAN (501-1061): 4.63e-147: 462: 33.16		LASP1_HUMAN (207-435): 2.59e-40: 148: 15.98
+	Hs
		601605 FGFR2_HUMAN (501-1065): 3.92e-155: 484: 33.11		ITSN2_HUMAN (166-444): 7.54e-12: 70.6: 14.13
+	Hs
		607971 FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89		LASP1_HUMAN (207-435): 2.59e-40: 148: 15.98
+	Hs
		508233 FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61		ITSN2_HUMAN (166-444): 7.54e-12: 70.6: 14.13
+	Hs
		508022 FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61		ITSN1_HUMAN (268-455): 5.42e-10: 64.5: 15.18
+	Hs
		339058 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		ITSN2_HUMAN (166-444): 7.54e-12: 70.6: 14.13
+	Hs
		338478 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		ITSN1_HUMAN (268-455): 5.42e-10: 64.5: 15.18
+	Hs
		607984 FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89		ITSN1_HUMAN (268-455): 5.42e-10: 64.5: 15.18