HitPredict

Interactor 1: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Interactor 2: CHM2B (Q9UQN3)
Charged multivesicular body protein 2b (CHMP2.5) (Chromatin-modifying protein 2b) (CHMP2b) (Vacuolar protein sorting-associated protein 2-2) (Vps2-2) (hVps2-2)
Gene: CHMP2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1114 Hs			1 213
+	Hs
		434285 RET_HUMAN (1-1114): 0: 1295: 100.00		CHM4B_HUMAN (12-200): 2.69e-30: 112: 21.03
+	At
		83719 Y5182_ARATH (190-1039): 0: 595: 14.94		VP601_ARATH (5-201): 3.77e-30: 112: 12.56
+	At
		96084 F4IB63_ARATH (249-1043): 0: 588: 13.73		VP601_ARATH (5-201): 3.77e-30: 112: 12.56
+	At
		1325548 Y5188_ARATH (227-1043): 0: 557: 14.24		VP601_ARATH (5-201): 3.77e-30: 112: 12.56
+	Hs
		339154 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		CHM2B_HUMAN (1-213): 4.88e-42: 142: 100.00
+	Hs
		608200 FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89		CHM2B_HUMAN (1-213): 4.88e-42: 142: 100.00
+	Hs
		338943 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		CHM4A_HUMAN (6-209): 7.25e-20: 85.6: 19.52
+	Hs
		608127 FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89		CHM4B_HUMAN (12-200): 2.69e-30: 112: 21.03