HitPredict

Interactor 1: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Interactor 2: FND3A (Q9Y2H6)
Fibronectin type-III domain-containing protein 3A (Human gene expressed in odontoblasts)
Gene: FNDC3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~fn3
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1114 Hs			1 1198
+	Hs
		434120 RET_HUMAN (1-1114): 0: 1295: 100.00		PTPRF_HUMAN (564-1183): 6.27e-77: 282: 14.69
+	Hs
		385283 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		NRCAM_HUMAN (154-1186): 2.1e-123: 414: 12.57
+	Hs
		507878 FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61		L1CAM_HUMAN (271-1195): 3.94e-80: 289: 12.93
+	Hs
		338012 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		L1CAM_HUMAN (271-1195): 3.94e-80: 289: 12.93
+	Hs
		383644 ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93		L1CAM_HUMAN (271-1195): 3.94e-80: 289: 12.93
+	Hs
		507980 FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61		PTPRS_HUMAN (559-1194): 2.52e-74: 274: 14.39
+	Hs
		337831 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		PTPRF_HUMAN (564-1183): 6.27e-77: 282: 14.69
+	Hs
		384360 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		L1CAM_HUMAN (271-1195): 3.94e-80: 289: 12.93
+	Hs
		384155 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		PTPRF_HUMAN (564-1183): 6.27e-77: 282: 14.69
+	Hs
		384777 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		PTPRS_HUMAN (559-1194): 2.52e-74: 274: 14.39
+	Rn
		984693 Q8K3F9_RAT (428-1113): 7.79e-134: 439: 24.10		L1CAM_RAT (268-1195): 4.45e-78: 283: 13.30
+	Rn
		984692 ERBB3_RAT (429-1105): 2.35e-126: 420: 21.41		L1CAM_RAT (268-1195): 4.45e-78: 283: 13.30
+	Hs
		337941 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		PTPRD_HUMAN (657-1184): 9.09e-61: 231: 13.37
+	Mm
		514127 FAK1_MOUSE (620-1076): 4.7e-105: 356: 27.04		L1CAM_MOUSE (268-1195): 4.95e-78: 283: 12.83
+	Hs
		1031989 NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19		PTPRS_HUMAN (559-1194): 2.52e-74: 274: 14.39
+	Hs
		337733 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		FINC_HUMAN (112-737): 5.66e-40: 164: 15.42
+	Hs
		383893 ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93		IGDC4_HUMAN (371-848): 1.35e-12: 74.7: 21.11
+	Hs
		338769 EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24		TITIN_HUMAN (12-282): 4.47e-09: 63.5: 8.99
+	Hs
		385252 NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69		TITIN_HUMAN (12-282): 4.47e-09: 63.5: 8.99