HitPredict

Interactor 1: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Interactor 2: FBX7 (Q9Y3I1)
F-box only protein 7
Gene: FBXO7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	27503909
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1114 Hs			1 522
+	Hs
		601621 FGFR2_HUMAN (501-1065): 3.92e-155: 484: 33.11		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		508285 FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		609625 FGFR3_HUMAN (501-1061): 4.63e-147: 462: 33.16		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		384044 ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93		FBX7_HUMAN (1-522): 0: 1102: 100.00