HitPredict

Interactor 1: TPM2 (P07951)
Tropomyosin beta chain (Beta-tropomyosin) (Tropomyosin-2)
Gene: TPM2

Interactor 2: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 298
+	Hs
		451193 TPM1_HUMAN (1-284): 4.27e-46: 158: 85.56		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		418881 TPM3_HUMAN (1-284): 1.59e-44: 154: 86.27		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		110795 H7BYY1_HUMAN (1-241): 2.86e-15: 75.3: 21.58		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		625341 TPM4_HUMAN (1-240): 6.77e-14: 71.4: 21.67		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		451218 TPM1_HUMAN (1-284): 4.27e-46: 158: 85.56		CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00
+	Hs
		418914 TPM3_HUMAN (1-284): 1.59e-44: 154: 86.27		CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00
+	Hs
		841153 TPM4_HUMAN (1-240): 6.77e-14: 71.4: 21.67		CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00