Interactor 1: TPM2 (P07951)
Tropomyosin beta chain (Beta-tropomyosin) (Tropomyosin-2)
Gene: TPM2

Interactor 2: TPM4 (P67936)
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
Gene: TPM4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 33961781, 34349018, 35235311
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Tropomyosin~Tropomyosin
Common GO terms GO:0005829 - cytosol
GO:0005862 - muscle thin filament tropomyosin
GO:0005884 - actin filament
GO:0006936 - muscle contraction
GO:0007015 - actin filament organization
and 4 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 284
Hs

1 248
+ Gg
+ Rn
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+ Hs
+ Gg
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+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024