Interactor 1: ERCC1 (P07992)
DNA excision repair protein ERCC-1
Gene: ERCC1
Interactor 2: XPF (Q92889)
DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4) (DNA repair protein complementing XP-F cells) (Xeroderma pigmentosum group F-complementing protein)
Gene: ERCC4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.993 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25538220, 21466675, 15932882, 22353549, 14734547, 21875596, 17912758, 16076955, 9013642, 23580445, 31495888, 8197175, 33961781, 14706347, 26186194, 24780295, 28514442, 24036546, 26453996, 11160918 and 8 others
more... |
| Identification Methods | two hybrid, pull down, affinity chromatography technology, x-ray crystallography, biochemical, fluorescent resonance energy transfer, nuclear magnetic resonance, molecular sieving, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ERCC4~HHH_5, ERCC4~Rad10 |
| Common GO terms | GO:0000109 - nucleotide-excision repair complex GO:0000110 - nucleotide-excision repair factor 1 complex GO:0000781 - chromosome, telomeric region GO:0001094 - TFIID-class transcription factor complex binding GO:0003684 - damaged DNA binding and 11 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
