HitPredict

Interactor 1: TSP1 (P07996)
Thrombospondin-1 (Glycoprotein G)
Gene: THBS1

Interactor 2: TFPI1 (P10646)
Tissue factor pathway inhibitor (TFPI) (Extrinsic pathway inhibitor) (EPI) (Lipoprotein-associated coagulation inhibitor) (LACI)
Gene: TFPI

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10922378
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004866 - endopeptidase inhibitor activity GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0005783 - endoplasmic reticulum GO:0009986 - cell surface
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1170 Hs			1 304
+	Hs
		393950 TSP1_HUMAN (1-1170): 0: 804: 100.00		A4_HUMAN (57-141): 4.05e-22: 98.4: 30.59
+	Hs
		434640 TSP1_HUMAN (1-1170): 0: 804: 100.00		CO7A1_HUMAN (121-177): 1.48e-20: 94.2: 38.33
+	Hs
		394219 TSP4_HUMAN (56-755): 1.29e-30: 133: 15.22		A4_HUMAN (57-141): 4.05e-22: 98.4: 30.59
+	Mm
		517683 SPON1_MOUSE (318-546): 8.01e-28: 123: 24.43		A4_MOUSE (57-141): 8.11e-23: 100: 30.59
+	Hs
		395815 SPON1_HUMAN (318-546): 5.06e-28: 124: 24.72		A4_HUMAN (57-141): 4.05e-22: 98.4: 30.59
+	Hs
		987552 SPON1_HUMAN (318-546): 5.06e-28: 124: 24.72		APLP2_HUMAN (106-176): 1.14e-21: 97.3: 29.58
+	Hs
		394121 TENX_HUMAN (199-513): 4.47e-26: 119: 10.60		A4_HUMAN (57-141): 4.05e-22: 98.4: 30.59
+	Hs
		394302 NOTC1_HUMAN (582-982): 2.84e-21: 103: 12.80		A4_HUMAN (57-141): 4.05e-22: 98.4: 30.59
+	Hs
		395555 NOTC4_HUMAN (198-700): 1.04e-14: 81.9: 12.12		A4_HUMAN (57-141): 4.05e-22: 98.4: 30.59
+	Hs
		395362 SORL_HUMAN (170-526): 1.23e-14: 81.5: 8.49		A4_HUMAN (57-141): 4.05e-22: 98.4: 30.59
+	Hs
		172657 LAMA5_HUMAN (496-717): 7.46e-09: 62.6: 14.22		CO7A1_HUMAN (121-177): 1.48e-20: 94.2: 38.33
+	Hs
		817020 SORL_HUMAN (170-526): 1.23e-14: 81.5: 8.49		TFPI2_HUMAN (15-100): 1.52e-10: 62.2: 30.23