Interactor 1: TSP1 (P07996)
Thrombospondin-1 (Glycoprotein G)
Gene: THBS1

Interactor 2: LRP1 (Q07954)
Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]
Gene: LRP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.845

The method score is based on:

Property Details
Experiments 14991768, 9045712, 7775583
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_3~EGF_CA, Ldl_recept_a~TSP_1, EGF_CA~TSP_3
Common GO terms GO:0005509 - calcium ion binding
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1170
Hs

1 4544
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024