HitPredict

Interactor 1: PBS2 (P08018)
MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B resistance protein 2) (Suppressor of fluoride sensitivity 4)
Gene: PBS2

Interactor 2: HSP73 (P09435)
Heat shock protein SSA3
Gene: SSA3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	11805837
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 668 Sc			1 649
+	Sc
		434724 PBS2_YEAST (1-668): 0: 581: 100.00		HSP72_YEAST (1-649): 0: 941: 78.89
+	Sc
		434723 PBS2_YEAST (1-668): 0: 581: 100.00		HSP71_YEAST (1-649): 0: 939: 79.35
+	Hs
		564066 PAK1_HUMAN (56-624): 3.98e-130: 396: 19.90		HSP76_HUMAN (4-649): 0: 950: 70.43
+	Hs
		504007 PAK1_HUMAN (56-624): 3.98e-130: 396: 19.90		HSP7C_HUMAN (2-649): 0: 946: 72.53
+	Hs
		564016 AKT1_HUMAN (311-655): 1.71e-126: 384: 21.75		HSP76_HUMAN (4-649): 0: 950: 70.43
+	Sc
		493046 YPK1_YEAST (56-665): 2.5e-126: 390: 16.82		HSP72_YEAST (1-649): 0: 941: 78.89
+	Hs
		503528 AKT1_HUMAN (311-655): 1.71e-126: 384: 21.75		HSP7C_HUMAN (2-649): 0: 946: 72.53
+	Sc
		490158 YPK1_YEAST (56-665): 2.5e-126: 390: 16.82		HSP71_YEAST (1-649): 0: 939: 79.35
+	Hs
		871551 PAK1_HUMAN (56-624): 3.98e-130: 396: 19.90		HSP72_HUMAN (2-610): 0: 927: 74.63
+	Mm
		926174 M3K14_MOUSE (153-619): 5.04e-110: 355: 23.24		HSP7C_MOUSE (2-649): 0: 946: 72.53
+	Hs
		713953 STK4_HUMAN (346-650): 5.8e-108: 337: 32.80		HS71L_HUMAN (2-649): 0: 958: 70.06
+	Hs
		564065 STK4_HUMAN (346-650): 5.8e-108: 337: 32.80		HSP76_HUMAN (4-649): 0: 950: 70.43
+	Hs
		503922 KPCE_HUMAN (261-665): 6.02e-105: 337: 23.83		HSP7C_HUMAN (2-649): 0: 946: 72.53
+	Hs
		503996 STK4_HUMAN (346-650): 5.8e-108: 337: 32.80		HSP7C_HUMAN (2-649): 0: 946: 72.53
+	Mm
		554912 KPCE_MOUSE (261-625): 2.28e-105: 338: 24.87		HS71A_MOUSE (2-649): 0: 943: 69.75
+	Hs
		503929 MP2K1_HUMAN (298-641): 1.87e-102: 319: 37.08		HSP7C_HUMAN (2-649): 0: 946: 72.53
+	Hs
		871550 STK4_HUMAN (346-650): 5.8e-108: 337: 32.80		HSP72_HUMAN (2-610): 0: 927: 74.63
+	Hs
		503561 MP2K2_HUMAN (358-641): 4.18e-75: 248: 41.59		HSP7C_HUMAN (2-649): 0: 946: 72.53
+	Hs
		483778 MP2K2_HUMAN (358-641): 4.18e-75: 248: 41.59		HS71B_HUMAN (2-649): 0: 936: 72.07
+	Hs
		734898 MP2K2_HUMAN (358-641): 4.18e-75: 248: 41.59		HSP72_HUMAN (2-610): 0: 927: 74.63