HitPredict

Interactor 1: PBS2 (P08018)
MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B resistance protein 2) (Suppressor of fluoride sensitivity 4)
Gene: PBS2

Interactor 2: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	11805837, 19536198, 16429126
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 668 Sc			1 613
+	Sc
		434761 PBS2_YEAST (1-668): 0: 581: 100.00		SSB2_YEAST (1-613): 0: 1118: 99.35
+	Sc
		510069 YPK1_YEAST (56-665): 2.5e-126: 390: 16.82		SSB1_YEAST (1-613): 0: 1128: 100.00
+	Sc
		520614 YPK1_YEAST (56-665): 2.5e-126: 390: 16.82		SSB2_YEAST (1-613): 0: 1118: 99.35
+	Hs
		564066 PAK1_HUMAN (56-624): 3.98e-130: 396: 19.90		HSP76_HUMAN (3-612): 0: 901: 58.66
+	Hs
		504007 PAK1_HUMAN (56-624): 3.98e-130: 396: 19.90		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		871551 PAK1_HUMAN (56-624): 3.98e-130: 396: 19.90		HSP72_HUMAN (4-612): 0: 891: 59.97
+	Hs
		564016 AKT1_HUMAN (311-655): 1.71e-126: 384: 21.75		HSP76_HUMAN (3-612): 0: 901: 58.66
+	Hs
		503528 AKT1_HUMAN (311-655): 1.71e-126: 384: 21.75		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Sc
		434720 PBS2_YEAST (1-668): 0: 581: 100.00		HSP73_YEAST (9-611): 0: 677: 60.66
+	Mm
		926174 M3K14_MOUSE (153-619): 5.04e-110: 355: 23.24		HSP7C_MOUSE (5-612): 0: 900: 59.84
+	Hs
		564065 STK4_HUMAN (346-650): 5.8e-108: 337: 32.80		HSP76_HUMAN (3-612): 0: 901: 58.66
+	Hs
		503922 KPCE_HUMAN (261-665): 6.02e-105: 337: 23.83		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		503996 STK4_HUMAN (346-650): 5.8e-108: 337: 32.80		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		713953 STK4_HUMAN (346-650): 5.8e-108: 337: 32.80		HS71L_HUMAN (5-612): 0: 896: 59.34
+	Mm
		554912 KPCE_MOUSE (261-625): 2.28e-105: 338: 24.87		HS71A_MOUSE (5-611): 0: 893: 59.44
+	Hs
		871550 STK4_HUMAN (346-650): 5.8e-108: 337: 32.80		HSP72_HUMAN (4-612): 0: 891: 59.97
+	Hs
		503929 MP2K1_HUMAN (298-641): 1.87e-102: 319: 37.08		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		503561 MP2K2_HUMAN (358-641): 4.18e-75: 248: 41.59		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		483778 MP2K2_HUMAN (358-641): 4.18e-75: 248: 41.59		HS71B_HUMAN (5-611): 0: 897: 59.93
+	Hs
		734898 MP2K2_HUMAN (358-641): 4.18e-75: 248: 41.59		HSP72_HUMAN (4-612): 0: 891: 59.97