HitPredict

Interactor 1: PBS2 (P08018)
MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B resistance protein 2) (Suppressor of fluoride sensitivity 4)
Gene: PBS2

Interactor 2: BEM1 (P29366)
Bud emergence protein 1 (Suppressor of RHO3 protein 1)
Gene: BEM1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	0.60	0.408

Property	Details
Experiments	21489982
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005934 - cellular bud tip GO:0005935 - cellular bud neck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 668 Sc			1 551
+	Sc
		420015 STE7_YEAST (348-650): 2.11e-45: 171: 36.39		BEM1_YEAST (1-551): 5.25e-139: 415: 100.00
+	Hs
		682191 AKT2_HUMAN (315-655): 1.72e-127: 387: 20.57		SH3R1_HUMAN (22-545): 5.41e-52: 192: 12.09
+	Hs
		681922 AKT1_HUMAN (311-655): 1.71e-126: 384: 21.75		SH3R1_HUMAN (22-545): 5.41e-52: 192: 12.09
+	Hs
		1026158 PAK1_HUMAN (56-624): 3.98e-130: 396: 19.90		ARHG7_HUMAN (131-542): 1.27e-45: 173: 12.01
+	Mm
		292047 PAK1_MOUSE (56-624): 8.62e-129: 392: 19.72		ARHG7_MOUSE (131-542): 2.3e-45: 173: 12.66
+	Hs
		1023039 STK4_HUMAN (346-650): 5.8e-108: 337: 32.80		SPTN1_HUMAN (84-543): 1.09e-62: 225: 14.34
+	Rn
		223051 PAK1_RAT (56-624): 1.22e-129: 395: 19.72		ARHG7_RAT (150-542): 1.82e-42: 163: 12.53
+	Hs
		209044 PAK1_HUMAN (56-624): 3.98e-130: 396: 19.90		NCK2_HUMAN (3-321): 4.29e-34: 134: 14.97
+	Hs
		557676 PAK1_HUMAN (56-624): 3.98e-130: 396: 19.90		NCK1_HUMAN (3-320): 8.34e-33: 131: 15.50
+	Mm
		292046 PAK1_MOUSE (56-624): 8.62e-129: 392: 19.72		NCK1_MOUSE (3-320): 1.79e-32: 130: 15.50
+	Hs
		298951 AKT2_HUMAN (315-655): 1.72e-127: 387: 20.57		SRBS2_HUMAN (37-215): 1.18e-27: 120: 18.59
+	Hs
		682008 AKT1_HUMAN (311-655): 1.71e-126: 384: 21.75		SRBS1_HUMAN (67-215): 2.96e-27: 119: 22.00
+	Rn
		223052 AKT3_RAT (339-638): 1.16e-102: 323: 24.27		ARHG7_RAT (150-542): 1.82e-42: 163: 12.53
+	Hs
		1026202 PAK1_HUMAN (56-624): 3.98e-130: 396: 19.90		SH3K1_HUMAN (33-133): 5.55e-13: 73.6: 19.23
+	Hs
		235479 AKT2_HUMAN (315-655): 1.72e-127: 387: 20.57		VINEX_HUMAN (37-215): 1.23e-09: 63: 16.32
+	Hs
		235471 KAPCA_HUMAN (322-666): 6.24e-127: 381: 22.16		VINEX_HUMAN (37-215): 1.23e-09: 63: 16.32
+	Hs
		800990 MP2K4_HUMAN (284-643): 5.06e-103: 321: 37.60		SH3R3_HUMAN (112-213): 2.39e-09: 62.1: 17.48
+	Mm
		1144396 MP2K2_MOUSE (358-641): 5.09e-75: 248: 41.46		NCK1_MOUSE (3-320): 1.79e-32: 130: 15.50
+	Dm
		1095512 HEP_DROME (349-658): 3.53e-43: 169: 36.83		Q86P80_DROME (20-429): 9.57e-46: 172: 12.47
+	Hs
		153151 MP2K7_HUMAN (350-643): 3.2e-54: 193: 38.05		SH3R3_HUMAN (112-213): 2.39e-09: 62.1: 17.48