HitPredict

Interactor 1: SPTA1 (P08032)
Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin)
Gene: SPTA1

Interactor 2: NMDE2 (Q01097)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B)
Gene: Grin2b

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	10862698
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2415 Mm			1 1482
+	Mm
		963773 ACTN2_MOUSE (1924-2414): 6.1e-54: 208: 29.28		NMDE2_MOUSE (1-1482): 0: 1874: 100.00
+	Hs
		725650 ACTN2_HUMAN (1924-2414): 4.23e-54: 208: 29.28		NMDE2_HUMAN (1-1482): 0: 1855: 98.38
+	Hs
		1028137 SPTN1_HUMAN (3-1269): 9.3e-39: 162: 18.50		NMDE2_HUMAN (1-1482): 0: 1855: 98.38
+	Mm
		963742 AKAP9_MOUSE (354-1057): 4.67e-09: 64.3: 9.49		NMDE2_MOUSE (1-1482): 0: 1874: 100.00
+	Hs
		1018891 SPTN1_HUMAN (3-1269): 9.3e-39: 162: 18.50		NMDE1_HUMAN (9-1482): 0: 1512: 52.38
+	Mm
		434795 SPTA1_MOUSE (1-2415): 0: 645: 100.00		NMDZ1_MOUSE (14-940): 0: 681: 23.41
+	Rn
		723638 ACTN1_RAT (1924-2414): 8.68e-57: 216: 29.28		NMDZ1_RAT (14-940): 0: 683: 23.52
+	Mm
		723613 ACTN2_MOUSE (1924-2414): 6.1e-54: 208: 29.28		NMDZ1_MOUSE (14-940): 0: 681: 23.41
+	Hs
		725646 ACTN2_HUMAN (1924-2414): 4.23e-54: 208: 29.28		NMDZ1_HUMAN (14-940): 0: 678: 23.52
+	Rn
		555251 SPTN1_RAT (2-1738): 3.8e-51: 203: 18.00		GRIA4_RAT (17-852): 0: 652: 21.12
+	Hs
		984260 SPTN1_HUMAN (3-1269): 9.3e-39: 162: 18.50		NMDZ1_HUMAN (14-940): 0: 678: 23.52
+	Hs
		786733 SPTN1_HUMAN (3-1269): 9.3e-39: 162: 18.50		GRIA2_HUMAN (8-871): 0: 677: 21.16
+	Rn
		585221 SPTN2_RAT (1280-2317): 6.33e-37: 156: 20.55		GRIA4_RAT (17-852): 0: 652: 21.12
+	Mm
		723587 SPTB2_MOUSE (1-626): 1.58e-20: 102: 20.56		NMDZ1_MOUSE (14-940): 0: 681: 23.41
+	Hs
		786728 SPTB2_HUMAN (1-626): 2.76e-20: 101: 20.56		GRIA2_HUMAN (8-871): 0: 677: 21.16
+	Mm
		723595 AKAP9_MOUSE (354-1057): 4.67e-09: 64.3: 9.49		NMDZ1_MOUSE (14-940): 0: 681: 23.41
+	Hs
		211568 ACTN4_HUMAN (1643-2165): 9.91e-10: 66.2: 20.45		NMDZ1_HUMAN (14-940): 0: 678: 23.52