HitPredict

Interactor 1: SP1 (P08047)
Transcription factor Sp1
Gene: SP1

Interactor 2: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22266860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0042803 - protein homodimerization activity
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 785 Hs			1 284
+	Hs
		418846 SP1_HUMAN (1-785): 7.23e-168: 506: 100.00		TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20
+	Hs
		434328 SP1_HUMAN (1-785): 7.23e-168: 506: 100.00		TPM2_HUMAN (1-284): 1.39e-38: 138: 85.56
+	Hs
		435121 SP1_HUMAN (1-785): 7.23e-168: 506: 100.00		MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67
+	Hs
		435035 SP1_HUMAN (1-785): 7.23e-168: 506: 100.00		TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72
+	Hs
		418949 KLF10_HUMAN (619-724): 8.57e-33: 134: 58.49		TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20
+	Hs
		931998 KLF10_HUMAN (619-724): 8.57e-33: 134: 58.49		TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72
+	Hs
		932043 KLF6_HUMAN (613-708): 5.24e-30: 122: 54.64		TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72
+	Hs
		418952 KLF9_HUMAN (650-712): 2.4e-11: 66.6: 44.62		TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20