Interactor 1: SP1 (P08047)
Transcription factor Sp1
Gene: SP1

Interactor 2: MK08 (P45983)
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)
Gene: MAPK8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 25398907, 19245816
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~zf-C2H2
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0010628 - positive regulation of gene expression
GO:0042826 - histone deacetylase binding
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 785
Hs

1 427
+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024