HitPredict

Interactor 1: SP1 (P08047)
Transcription factor Sp1
Gene: SP1

Interactor 2: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	16943418, 18258854
Identification Methods	affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Pkinase~zf-C2H2
Common GO terms	GO:0005737 - cytoplasm GO:0032869 - cellular response to insulin stimulus GO:0046872 - metal ion binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 785 Hs			1 592
+	Hs
		435062 SP1_HUMAN (1-785): 7.23e-168: 506: 100.00		KPCD_HUMAN (85-585): 1.92e-177: 519: 36.26
+	Hs
		434969 SP1_HUMAN (1-785): 7.23e-168: 506: 100.00		AKT1_HUMAN (172-582): 1.55e-153: 451: 36.39
+	Hs
		681798 SP3_HUMAN (54-712): 1.31e-111: 359: 38.96		AKT1_HUMAN (172-582): 1.55e-153: 451: 36.39
+	Hs
		67850 ZN724_HUMAN (317-553): 2.18e-46: 177: 6.58		KAPCA_HUMAN (219-578): 5.07e-143: 419: 33.06
+	Hs
		568688 SP6_HUMAN (557-708): 9.79e-39: 149: 50.64		KAPCA_HUMAN (219-578): 5.07e-143: 419: 33.06
+	Hs
		157880 KLF11_HUMAN (619-735): 1.62e-33: 137: 55.56		KS6A3_HUMAN (168-539): 2.67e-105: 335: 20.47