HitPredict

Interactor 1: SP1 (P08047)
Transcription factor Sp1
Gene: SP1

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.765

The method score is based on:

Property Details
Experiments 23714681, 24530506, 28425985, 32115405, 10899165, 16734381, 16478997, 12200149, 10651903, 17906698, 31536933, 15647279, 34252870, 19062177, 11517158, 11030335, 17623675, 22415975
Identification Methods affinity chromatography technology, enzymatic study, pull down, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0001221 - transcription coregulator binding
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 6 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 785
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Last updated: 15 Jul 2024