Interactor 1: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R
Interactor 2: GHR (P10912)
Growth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)]
Gene: GHR
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15044591 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EpoR_lig-bind~fn3, fn3~fn3, Furin-like~fn3, PK_Tyr_Ser-Thr~fn3, Recep_L_domain~fn3 |
| Common GO terms | GO:0005886 - plasma membrane GO:0016020 - membrane GO:0043025 - neuronal cell body GO:0043235 - receptor complex GO:0048009 - insulin-like growth factor receptor signaling pathway |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
 |
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
