Interactor 1: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Interactor 2: IBP3 (P17936)
Insulin-like growth factor-binding protein 3 (IBP-3) (IGF-binding protein 3) (IGFBP-3)
Gene: IGFBP3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 9389554
Identification Methods biochemical
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005520 - insulin-like growth factor binding
GO:0031994 - insulin-like growth factor I binding
GO:0043410 - positive regulation of MAPK cascade
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1367
Hs

1 291
+ Rn
+ Hs
+ Hs
+ Hs
+ Dr

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Last updated: 15 Jul 2024