Interactor 1: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R
Interactor 2: RASA1 (P20936)
Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP)
Gene: RASA1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.53 | 1.00 | 0.734 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 7642582 |
| Identification Methods | affinity chromatography technology, pull down |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SH2~fn3, PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1 |
| Common GO terms | GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0043066 - negative regulation of apoptotic process |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
