HitPredict

Interactor 1: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Interactor 2: DPP4 (P27487)
Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)]
Gene: DPP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	34709727
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0008284 - positive regulation of cell population proliferation GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1367 Hs			1 766
+	Hs
		411304 INSR_HUMAN (32-1365): 0: 1219: 56.54		DPP4_HUMAN (1-766): 0: 862: 100.00
+	Hs
		648772 EPHA7_HUMAN (656-1342): 1.15e-177: 555: 23.39		DPP4_HUMAN (1-766): 0: 862: 100.00
+	Hs
		385091 NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61		DPP9_HUMAN (81-763): 0: 544: 21.45
+	Hs
		384193 NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61		ACPH_HUMAN (202-764): 1.4e-104: 338: 13.83
+	Hs
		384465 NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61		PPCE_HUMAN (206-765): 1.04e-92: 306: 14.16