HitPredict

Interactor 1: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Interactor 2: DDRGK (Q96HY6)
DDRGK domain-containing protein 1 (Dashurin) (UFM1-binding and PCI domain-containing protein 1)
Gene: DDRGK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008284 - positive regulation of cell population proliferation GO:0030335 - positive regulation of cell migration GO:0043066 - negative regulation of apoptotic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1367 Hs			1 314
+	Hs
		411470 INSR_HUMAN (32-1365): 0: 1219: 56.54		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		665514 EPHA8_HUMAN (655-1337): 4.83e-169: 533: 23.87		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		1294127 ALK_HUMAN (939-1304): 2.51e-75: 278: 39.12		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		508150 FGFR1_HUMAN (972-1266): 1.32e-64: 238: 39.54		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		1081567 NTRK3_HUMAN (977-1262): 5.74e-64: 236: 39.16		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		445868 ROS1_HUMAN (691-919): 7.36e-11: 69.4: 17.47		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00