HitPredict

Interactor 1: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Interactor 2: SDF2L (Q9HCN8)
Stromal cell-derived factor 2-like protein 1 (SDF2-like protein 1) (PWP1-interacting protein 8)
Gene: SDF2L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.618

Property	Details
Experiments	33961781, 35384245
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1367 Hs			1 221
+	Hs
		411500 INSR_HUMAN (32-1365): 0: 1219: 56.54		SDF2L_HUMAN (1-221): 4.34e-95: 278: 100.00
+	Hs
		411482 INSR_HUMAN (32-1365): 0: 1219: 56.54		SDF2_HUMAN (26-221): 1.48e-84: 251: 65.15
+	Hs
		872580 EPHB4_HUMAN (648-1305): 5.48e-162: 514: 23.20		SDF2L_HUMAN (1-221): 4.34e-95: 278: 100.00
+	Hs
		1336439 ALK_HUMAN (939-1304): 2.51e-75: 278: 39.12		SDF2L_HUMAN (1-221): 4.34e-95: 278: 100.00
+	Hs
		674533 UFO_HUMAN (790-1271): 9.27e-68: 249: 32.10		SDF2L_HUMAN (1-221): 4.34e-95: 278: 100.00
+	Hs
		1081611 NTRK3_HUMAN (977-1262): 5.74e-64: 236: 39.16		SDF2L_HUMAN (1-221): 4.34e-95: 278: 100.00
+	Hs
		609551 FGFR3_HUMAN (972-1266): 2.05e-63: 234: 38.44		SDF2L_HUMAN (1-221): 4.34e-95: 278: 100.00
+	Hs
		1081576 NTRK3_HUMAN (977-1262): 5.74e-64: 236: 39.16		SDF2_HUMAN (26-221): 1.48e-84: 251: 65.15
+	Hs
		445879 ROS1_HUMAN (691-919): 7.36e-11: 69.4: 17.47		SDF2L_HUMAN (1-221): 4.34e-95: 278: 100.00
+	Hs
		445873 ROS1_HUMAN (691-919): 7.36e-11: 69.4: 17.47		SDF2_HUMAN (26-221): 1.48e-84: 251: 65.15