HitPredict

Interactor 1: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Interactor 2: DJB11 (Q9UBS4)
DnaJ homolog subfamily B member 11 (APOBEC1-binding protein 2) (ABBP-2) (DnaJ protein homolog 9) (ER-associated DNAJ) (ER-associated Hsp40 co-chaperone) (Endoplasmic reticulum DNA J domain-containing protein 3) (ER-resident protein ERdj3) (ERdj3) (ERj3p) (HEDJ) (Human DnaJ protein 9) (hDj-9) (PWP1-interacting protein 4)
Gene: DNAJB11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1367 Hs			1 358
+	Hs
		435551 IGF1R_HUMAN (1-1367): 0: 1387: 100.00		DNJA1_HUMAN (20-356): 3.06e-116: 344: 31.88
+	Hs
		243262 IGF1R_HUMAN (1-1367): 0: 1387: 100.00		DNJA2_HUMAN (21-349): 3.9e-113: 336: 34.35
+	Hs
		411515 INSR_HUMAN (32-1365): 0: 1219: 56.54		DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00
+	Hs
		537779 INSRR_HUMAN (14-1310): 0: 1170: 55.26		DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00
+	Hs
		411313 INSR_HUMAN (32-1365): 0: 1219: 56.54		DNJA1_HUMAN (20-356): 3.06e-116: 344: 31.88
+	Hs
		243254 INSR_HUMAN (32-1365): 0: 1219: 56.54		DNJA2_HUMAN (21-349): 3.9e-113: 336: 34.35
+	Dm
		448256 INSR_DROME (12-1356): 0: 910: 32.97		Q9VFV9_DROME (26-328): 7.17e-40: 147: 33.53
+	Hs
		665541 EPHA8_HUMAN (655-1337): 4.83e-169: 533: 23.87		DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00
+	Hs
		1354290 ALK_HUMAN (939-1304): 2.51e-75: 278: 39.12		DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00
+	Hs
		666658 LTK_HUMAN (989-1319): 5.64e-75: 270: 40.11		DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00
+	Hs
		385658 NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61		DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00
+	Hs
		169212 MUSK_HUMAN (993-1262): 8.25e-69: 251: 42.96		DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00
+	Hs
		674554 UFO_HUMAN (790-1271): 9.27e-68: 249: 32.10		DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00
+	Hs
		243669 ALK_HUMAN (939-1304): 2.51e-75: 278: 39.12		DNJA2_HUMAN (21-349): 3.9e-113: 336: 34.35
+	Hs
		384352 NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61		DNJA1_HUMAN (20-356): 3.06e-116: 344: 31.88
+	Hs
		674347 UFO_HUMAN (790-1271): 9.27e-68: 249: 32.10		DNJA1_HUMAN (20-356): 3.06e-116: 344: 31.88
+	Hs
		243251 NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61		DNJA2_HUMAN (21-349): 3.9e-113: 336: 34.35
+	Hs
		243305 UFO_HUMAN (790-1271): 9.27e-68: 249: 32.10		DNJA2_HUMAN (21-349): 3.9e-113: 336: 34.35
+	Hs
		384289 NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61		DNJB1_HUMAN (23-344): 5.46e-108: 321: 30.41
+	Hs
		636250 UFO_HUMAN (790-1271): 9.27e-68: 249: 32.10		DNJB1_HUMAN (23-344): 5.46e-108: 321: 30.41