HitPredict

Interactor 1: HCK (P08103)
Tyrosine-protein kinase HCK (EC 2.7.10.2) (B-cell/myeloid kinase) (BMK) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p56-HCK/p59-HCK)
Gene: HCK

Interactor 2: FCGR1 (P26151)
High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I) (Fc-gamma RI) (FcRI) (CD antigen CD64)
Gene: FCGR1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380812
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045087 - innate immune response
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 524 Mm			1 404
+	Hs
		442771 HCK_HUMAN (1-524): 0: 646: 89.54		FCGR1_HUMAN (115-387): 8.36e-30: 120: 15.83
+	Hs
		519400 SRC_HUMAN (26-522): 0: 596: 57.11		FCERA_HUMAN (95-330): 9.83e-38: 138: 20.99
+	Hs
		412047 FYN_HUMAN (11-522): 0: 600: 56.39		FCG2B_HUMAN (111-395): 2.11e-30: 120: 17.83
+	Hs
		412048 FYN_HUMAN (11-522): 0: 600: 56.39		FCG2C_HUMAN (111-349): 3.4e-30: 120: 17.16
+	Hs
		522811 SRC_HUMAN (26-522): 0: 596: 57.11		FCG2B_HUMAN (111-395): 2.11e-30: 120: 17.83
+	Hs
		522812 SRC_HUMAN (26-522): 0: 596: 57.11		FCG2C_HUMAN (111-349): 3.4e-30: 120: 17.16
+	Hs
		434019 LYN_HUMAN (22-524): 0: 572: 70.12		ROBO2_HUMAN (2-330): 2.62e-36: 143: 12.95
+	Hs
		411560 LCK_HUMAN (22-524): 0: 586: 63.87		FCG3A_HUMAN (109-335): 1.38e-32: 124: 17.17
+	Mm
		639452 LYN_MOUSE (22-524): 0: 572: 70.31		FCRL5_MOUSE (13-404): 3.93e-34: 135: 17.10
+	Hs
		523211 SRC_HUMAN (26-522): 0: 596: 57.11		TUTLB_HUMAN (21-303): 2.13e-24: 107: 12.46
+	Hs
		433610 LYN_HUMAN (22-524): 0: 572: 70.12		FCG2B_HUMAN (111-395): 2.11e-30: 120: 17.83
+	Hs
		433545 LYN_HUMAN (22-524): 0: 572: 70.12		FCG2A_HUMAN (111-299): 4.1e-30: 119: 17.99
+	Hs
		433507 YES_HUMAN (22-522): 0: 582: 57.51		TUTLB_HUMAN (21-303): 2.13e-24: 107: 12.46
+	Hs
		434081 LYN_HUMAN (22-524): 0: 572: 70.12		TUTLB_HUMAN (21-303): 2.13e-24: 107: 12.46
+	Hs
		434111 LYN_HUMAN (22-524): 0: 572: 70.12		ROBO1_HUMAN (195-371): 1.28e-23: 105: 13.85
+	Dm
		219802 ABL_DROME (52-517): 2.4e-171: 527: 40.34		O44924_DROME (20-288): 3.04e-34: 137: 14.01
+	Hs
		433569 LYN_HUMAN (22-524): 0: 572: 70.12		CD22_HUMAN (79-304): 2.87e-18: 89.1: 14.96
+	Hs
		523003 SRC_HUMAN (26-522): 0: 596: 57.11		MYLK_HUMAN (25-110): 3.34e-09: 60.9: 14.43
+	Hs
		789014 TEC_HUMAN (3-518): 1.84e-163: 479: 34.92		TUTLB_HUMAN (21-303): 2.13e-24: 107: 12.46