HitPredict

Interactor 1: HCK (P08103)
Tyrosine-protein kinase HCK (EC 2.7.10.2) (B-cell/myeloid kinase) (BMK) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p56-HCK/p59-HCK)
Gene: HCK

Interactor 2: DVL2 (Q60838)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19920076
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 524 Mm			1 736
+	Mm
		403438 SRC_MOUSE (26-522): 0: 595: 57.52		DVL2_MOUSE (13-736): 0: 541: 100.00
+	Hs
		150821 YES_HUMAN (22-522): 0: 582: 57.51		DVL2_HUMAN (1-736): 3.28e-180: 534: 96.60
+	Hs
		150822 LYN_HUMAN (22-524): 0: 572: 70.12		DVL2_HUMAN (1-736): 3.28e-180: 534: 96.60
+	Hs
		150807 ABL1_HUMAN (42-521): 6.91e-176: 527: 39.34		DVL2_HUMAN (1-736): 3.28e-180: 534: 96.60
+	Dm
		337649 ABL_DROME (52-517): 2.4e-171: 527: 40.34		DSH_DROME (6-563): 1.52e-117: 368: 46.05
+	Ce
		106665 SRC1_CAEEL (22-523): 3.41e-178: 513: 43.23		Q18239_CAEEL (14-644): 1.26e-85: 288: 28.53
+	Hs
		412246 FYN_HUMAN (11-522): 0: 600: 56.39		RIMS1_HUMAN (85-722): 4.93e-50: 192: 13.83
+	Mm
		411930 LCK_MOUSE (22-524): 0: 593: 64.06		DLG1_MOUSE (95-708): 1.25e-48: 186: 15.46
+	Hs
		522873 SRC_HUMAN (26-522): 0: 596: 57.11		AFAD_HUMAN (261-701): 1.31e-43: 172: 19.40
+	Hs
		411698 LCK_HUMAN (22-524): 0: 586: 63.87		DLG1_HUMAN (95-708): 2.54e-46: 179: 15.96
+	Hs
		412412 FYN_HUMAN (11-522): 0: 600: 56.39		RIMS2_HUMAN (75-720): 1.7e-40: 162: 12.58
+	Hs
		433300 YES_HUMAN (22-522): 0: 582: 57.51		AFAD_HUMAN (261-701): 1.31e-43: 172: 19.40
+	Hs
		433731 LYN_HUMAN (22-524): 0: 572: 70.12		DLG1_HUMAN (95-708): 2.54e-46: 179: 15.96
+	Hs
		433666 LYN_HUMAN (22-524): 0: 572: 70.12		AFAD_HUMAN (261-701): 1.31e-43: 172: 19.40
+	Hs
		434083 LYN_HUMAN (22-524): 0: 572: 70.12		RIMS2_HUMAN (75-720): 1.7e-40: 162: 12.58
+	Hs
		337498 ABL1_HUMAN (42-521): 6.91e-176: 527: 39.34		RIMS1_HUMAN (85-722): 4.93e-50: 192: 13.83
+	Hs
		412128 FYN_HUMAN (11-522): 0: 600: 56.39		DLG4_HUMAN (199-494): 4.13e-22: 103: 15.82
+	Mm
		403445 SRC_MOUSE (26-522): 0: 595: 57.52		DLG4_MOUSE (199-494): 3.53e-22: 103: 15.82
+	Hs
		411696 LCK_HUMAN (22-524): 0: 586: 63.87		PTN13_HUMAN (91-442): 1.61e-14: 80.1: 14.37
+	Hs
		433729 LYN_HUMAN (22-524): 0: 572: 70.12		PTN13_HUMAN (91-442): 1.61e-14: 80.1: 14.37