HitPredict

Interactor 1: ENPL (P08110)
Endoplasmin (Heat shock 108 kDa protein) (HSP 108) (HSP108) (Heat shock protein 90 kDa beta member 1) (Transferrin-binding protein)
Gene: HSP90B1

Interactor 2: BRAF (Q04982)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (Proto-oncogene c-Rmil) (Serine/threonine-protein kinase Rmil)
Gene: BRAF

Species: Gallus gallus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27034005
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 795 Gg			1 766
+	Hs
		538082 ENPL_HUMAN (1-795): 0: 1047: 89.04		BRAF_HUMAN (1-766): 0: 754: 93.89
+	Mm
		435915 ENPL_MOUSE (1-782): 0: 1043: 89.66		BRAF_MOUSE (9-766): 0: 713: 89.74
+	Hs
		437860 HS90B_HUMAN (74-776): 0: 983: 46.54		BRAF_HUMAN (1-766): 0: 754: 93.89
+	Hs
		431496 HS90A_HUMAN (69-776): 0: 975: 46.03		BRAF_HUMAN (1-766): 0: 754: 93.89
+	Hs
		373626 ENPL_HUMAN (1-795): 0: 1047: 89.04		RAF1_HUMAN (100-755): 0: 577: 54.33
+	Hs
		373549 HS90B_HUMAN (74-776): 0: 983: 46.54		RAF1_HUMAN (100-755): 0: 577: 54.33
+	Hs
		373543 HS90A_HUMAN (69-776): 0: 975: 46.03		RAF1_HUMAN (100-755): 0: 577: 54.33
+	Hs
		488555 ENPL_HUMAN (1-795): 0: 1047: 89.04		ARAF_HUMAN (143-750): 1.58e-165: 492: 55.88
+	Hs
		437832 HS90B_HUMAN (74-776): 0: 983: 46.54		ARAF_HUMAN (143-750): 1.58e-165: 492: 55.88
+	Hs
		438028 HS90B_HUMAN (74-776): 0: 983: 46.54		EPHB1_HUMAN (101-747): 7.19e-159: 488: 18.57
+	Hs
		431459 HS90A_HUMAN (69-776): 0: 975: 46.03		ARAF_HUMAN (143-750): 1.58e-165: 492: 55.88
+	Hs
		431691 HS90A_HUMAN (69-776): 0: 975: 46.03		EPHB1_HUMAN (101-747): 7.19e-159: 488: 18.57
+	Hs
		431562 HS90A_HUMAN (69-776): 0: 975: 46.03		EPHA3_HUMAN (104-752): 3.52e-153: 473: 18.31
+	Hs
		438029 HS90B_HUMAN (74-776): 0: 983: 46.54		EPHA4_HUMAN (107-747): 1.41e-147: 458: 19.03
+	Hs
		437892 HS90B_HUMAN (74-776): 0: 983: 46.54		EPHA1_HUMAN (120-757): 3.9e-135: 425: 18.93
+	Hs
		437918 HS90B_HUMAN (74-776): 0: 983: 46.54		EPHA2_HUMAN (120-766): 1.72e-132: 419: 18.47
+	Hs
		431531 HS90A_HUMAN (69-776): 0: 975: 46.03		EPHA1_HUMAN (120-757): 3.9e-135: 425: 18.93
+	Hs
		431561 HS90A_HUMAN (69-776): 0: 975: 46.03		EPHA2_HUMAN (120-766): 1.72e-132: 419: 18.47
+	Hs
		438332 HS90B_HUMAN (74-776): 0: 983: 46.54		KSR1_HUMAN (232-732): 1.22e-111: 362: 25.62
+	Hs
		438285 HS90B_HUMAN (74-776): 0: 983: 46.54		KSR2_HUMAN (449-731): 1.19e-46: 181: 36.52