HitPredict

Interactor 1: ENPL (P08113)
Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Endoplasmic reticulum resident protein 99) (ERp99) (Heat shock protein 90 kDa beta member 1) (Polymorphic tumor rejection antigen 1) (Tumor rejection antigen gp96)
Gene: Hsp90b1

Interactor 2: BIP (P20029)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: Hspa5

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

The method score is based on:

Property	Details
Experiments	12475965, 19805157
Identification Methods	biochemical, anti bait coimmunoprecipitation
Interaction Type	association, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005576 - extracellular region GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0005789 - endoplasmic reticulum membrane and 11 others more... GO:0005790 - smooth endoplasmic reticulum GO:0005829 - cytosol GO:0016887 - ATP hydrolysis activity GO:0030496 - midbody GO:0034663 - endoplasmic reticulum chaperone complex GO:0036503 - ERAD pathway GO:0042470 - melanosome GO:0043066 - negative regulation of apoptotic process GO:0044183 - protein folding chaperone GO:0051082 - unfolded protein binding GO:0140662 - ATP-dependent protein folding chaperone
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1	802
Mm

1	655

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024