HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 758
+	Hs
		496717 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496789 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496691 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496760 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496684 RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		498148 RHOA_MOUSE (1-193): 7.11e-82: 242: 92.23		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Mm
		498009 RHOG_MOUSE (1-193): 3.54e-78: 233: 54.92		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		653946 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56
+	Hs
		297820 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		K0754_HUMAN (5-450): 2.95e-22: 105: 11.86
+	Hs
		297823 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		K0754_HUMAN (5-450): 2.95e-22: 105: 11.86
+	Hs
		297809 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		K0754_HUMAN (5-450): 2.95e-22: 105: 11.86
+	Ce
		136793 RAC1_CAEEL (1-193): 2.88e-81: 241: 53.89		UNC89_CAEEL (4-459): 4.47e-21: 101: 12.37
+	Hs
		297827 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		K0754_HUMAN (5-450): 2.95e-22: 105: 11.86
+	Ce
		104464 G5EBV3_CAEEL (2-193): 4.06e-79: 235: 50.52		UNC89_CAEEL (4-459): 4.47e-21: 101: 12.37
+	Hs
		297812 RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12		K0754_HUMAN (5-450): 2.95e-22: 105: 11.86
+	Hs
		297822 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		K0754_HUMAN (5-450): 2.95e-22: 105: 11.86
+	Hs
		297819 RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54		K0754_HUMAN (5-450): 2.95e-22: 105: 11.86
+	Ce
		136794 CDC42_CAEEL (1-193): 1.06e-75: 226: 49.74		UNC89_CAEEL (4-459): 4.47e-21: 101: 12.37
+	Ce
		136800 RHO1_CAEEL (1-192): 1.4e-75: 226: 83.33		UNC89_CAEEL (4-459): 4.47e-21: 101: 12.37
+	Hs
		894572 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		MUC12_HUMAN (15-752): 1.81e-12: 73.5: 8.54