HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	21319273
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 298
+	Hs
		625333 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		900381 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		CDK5_HUMAN (1-292): 1.62e-138: 394: 59.39
+	Hs
		925197 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		CDK5_HUMAN (1-292): 1.62e-138: 394: 59.39
+	Hs
		950926 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		CDK5_HUMAN (1-292): 1.62e-138: 394: 59.39
+	Hs
		893906 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		CDK5_HUMAN (1-292): 1.62e-138: 394: 59.39
+	Hs
		545324 RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12		CDK5_HUMAN (1-292): 1.62e-138: 394: 59.39
+	Hs
		915609 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		CDK5_HUMAN (1-292): 1.62e-138: 394: 59.39
+	Hs
		892319 RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54		CDK5_HUMAN (1-292): 1.62e-138: 394: 59.39
+	Hs
		915610 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		CDK16_HUMAN (1-286): 4.1e-107: 322: 55.40