HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: MRP1 (P33527)
Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter)
Gene: ABCC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 1531
+	Hs
		706695 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		MRP1_HUMAN (1-1531): 0: 1288: 100.00
+	Hs
		706702 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		MRP1_HUMAN (1-1531): 0: 1288: 100.00
+	Hs
		706705 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		MRP1_HUMAN (1-1531): 0: 1288: 100.00
+	Hs
		706693 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		MRP1_HUMAN (1-1531): 0: 1288: 100.00
+	Hs
		545225 RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12		MRP1_HUMAN (1-1531): 0: 1288: 100.00
+	Hs
		706700 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		MRP1_HUMAN (1-1531): 0: 1288: 100.00
+	Hs
		706692 RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54		MRP1_HUMAN (1-1531): 0: 1288: 100.00
+	Sc
		419697 RHO1_YEAST (3-179): 1.62e-95: 278: 74.01		YCFI_YEAST (27-1531): 0: 980: 38.73
+	Hs
		179403 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		MRP5_HUMAN (201-1524): 0: 840: 32.39
+	Hs
		179406 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		MRP5_HUMAN (201-1524): 0: 840: 32.39
+	Hs
		179391 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		MRP5_HUMAN (201-1524): 0: 840: 32.39
+	Hs
		179408 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		MRP5_HUMAN (201-1524): 0: 840: 32.39
+	Hs
		179401 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		MRP5_HUMAN (201-1524): 0: 840: 32.39
+	Hs
		179393 RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12		MRP5_HUMAN (201-1524): 0: 840: 32.39
+	Hs
		179405 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		MRP5_HUMAN (201-1524): 0: 840: 32.39
+	Hs
		179400 RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54		MRP5_HUMAN (201-1524): 0: 840: 32.39