HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.962

The method score is based on:

Property Details
Experiments 28514442, 33961781, 31871319, 35271311, 31980649, 36652389, unassigned2173
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~Ras
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
and 11 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 193
Hs

1 193
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024